pH-Responsive Co-Delivery Nanoparticles

Synergistically reverses MDR

Ortho ester-modified carrier triggers drug release in acidic tumor environment, reversing resistance with anti-inflammatory agent

Li, Junnan · Junjie, Hu · Ying, Zhou · Yuping, Yang · Tang, Rupei · Wang, Xin

Journal of Drug Delivery Science and Technology 2024

Specifications

肿瘤抑制率

{'zh': '83.70', 'en': ''} %

Advantages

Effectively triggered drug release under tumor acidic conditions

Significantly increased intracellular drug concentration in resistant cells