Neutrophil Membrane-Cloaked Nanoparticles

Enhanced Plaque Targeting

These nanoparticles mimic neutrophil function to achieve efficient targeting of atherosclerotic plaques and deliver simvastatin to suppress local inflammation.

Zhang, Ningnannan · Zhang, Tianzhu · Feng, Jintang · Jian, Shang · Beibei, Zhang · Dong, Qingyang · Zhang, Zhang · Sun, Chunyang

Materials Today Bio 2025

Specifications

Plaque area reduced

{'zh': '', 'en': '1.48'} %

Advantages

Significantly decreased macrophage-mediated phagocytosis

Achieved better plaque targeting in ApoE−/− mice