Targets pyroptosis in prostatitis
Inhibits GSDMD-mediated prostate epithelial cell pyroptosis, improving experimental autoimmune prostatitis with a clear mechanism and ready drug availability.
Chen, Lei · Liu, Yi · Shaoyu, Yue · Wang, Hui · Chen, Jia · Chen, Xianguo · Li Li, Zhang · Liang, Chaozhao
International Journal of Biological Sciences 2024
Disulfiram effectively improves experimental autoimmune prostatitis
Highly expressed in prostate tissues of BPH patients with inflammation
P2X7R, NEK7, and GSDMD-NT highly expressed in prostate epithelial cells