Conducting Polymer Composite Electrode

4× Signal, 500× Anti-interference

A nanostructured composite electrode based on functionalized MWCNTs and poly(amino-triazole) that overcomes signal instability of bare electrodes for caffeoylquinic acid detection, offering selective sensing with a fourfold current increase.

Shen, Jian · Dai, Jindong · Muthusamy, Selvaraj · Kannan, Palanisamy · Zhu, Dongwei · You, Benshuai · Liu, Xiaotian

Food Chemistry 2025

Specifications

Sensitivity enhancement

{'zh': '4', 'en': '4'}

Linear range

{'zh': '0.1-200', 'en': '0.1-200'} μM

Limit of detection

{'zh': '30', 'en': '30'} nM

Selectivity: maximum tolerable caffeine

{'zh': '500', 'en': '500'} 倍

Advantages

Signal stabilized

Overcomes signal decay caused by deposition of oxidation products, yielding a reproducible response.

Caffeine-resistant

Selective determination of 3-CQA is achieved even in the presence of 500 times the concentration of caffeine, enabling direct analysis of real samples like coffee and tea.

LOD of 30 nM

Sensitivity is sufficient for trace 3-CQA, applicable to low-concentration samples such as blood.

Applications

• Food Quality Testing：Direct detection of 3-CQA in coffee, tea, and other foods without complex pretreatment.
• Blood Biomarker Detection：For trace 3-CQA in blood, aiding assessment of glucose metabolism.
• Electrochemical Sensors：Provides a selective and stable modified electrode, extensible to other phenolic acids.
• Polyphenol Analysis：Achieves specific recognition of 3-CQA among polyphenols, avoiding interference from structural analogues.