Wearable TTFields Device

Backpack-portable therapy

A wearable tumor treating fields device that integrates bulky benchtop components into a backpack form, enabling patients to receive therapy during daily activities; animal studies confirm inhibition of breast cancer progression.

Yanyu, Zheng · Ying, Zhu · Xie, Xu · Pan, Yun · Chen, Weidong · Zhang, Shaomin · Wang, Minmin

Breast Cancer: Targets and Therapy 2026

Specifications

Maximum output voltage

{'zh': '55', 'en': '55'} V

Maximum output current

{'zh': '40', 'en': '40'} mA

Frequency bandwidth

{'zh': '0~250', 'en': '0~250'} kHz

In vivo electric field intensity

{'zh': '1-1.5', 'en': '1-1.5'} V/cm

Advantages

Backpack wearable

The device is integrated into a backpack, freeing patients from benchtop equipment and enabling treatment during daily activities, potentially improving adherence.

Wide output range

The device outputs approximately 55 V, 0–250 kHz, up to 40 mA, covering the parameter needs of various tumor types.

In vivo tumor suppression

In rat breast cancer models, 24-hour daily treatment for 7 days significantly downregulated ki67 mRNA, upregulated Bax, and downregulated Bcl2 protein, proving tumor progression inhibition.

Applications

• Wearable medical devices：Backpack design integrates TTFields into daily wear, reducing hospital dependence.
• Tumor treating fields therapy：As a new TTFields device, it provides a non-invasive breast cancer treatment option.
• Portable medical devices：Lightweight and portable, suitable for long-term out-of-hospital treatment.