targeting mitochondria against lung cancer
This resveratrol dimer selectively induces apoptosis in lung cancer cells by triggering mitochondrial membrane potential reduction and ROS elevation.
Yin, Ruochun · Zhang, Yilong · Su, Lining · Chen, Dongdong · Lou, Shidi · Wang, Lin · Tang, Rupei · Zhang, Liang · Tian, Xiaohe
Frontiers in Pharmacology 2023
Induces mitochondrial membrane potential (ΔΨm) reduction in A549 cells
Increases intracellular reactive oxygen species (ROS) levels
Leads to apoptosis